THE EFFECTS OF 6-MERCAPTOPURINE ON BIOSYNTHESIS IN ESCHERICHIA COLI
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چکیده
منابع مشابه
The effects of 6-mercaptopurine on biosynthesis in Escherichia coli.
The purine analogue, 6-mercaptopurine (6-MP) (l), has been the subject of considerable study, but the mechanisms of its actions are still not clear. This drug inhibits the proliferation of acute and chronic myelocytic leucemias (2) and the growth of bacteria (3). It interferes with the utilization of formate for nucleic acid synthesis (4) and suppresses the formation of adaptive enzymes (5). Ho...
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Metabolism of 6-Mercaptopurine by Resistant Escherichia coli Cells.
Coggin, Joseph H. (University of Chicago, Chicago, Ill.), Muriel Loosemore, and William R. Martin. Metabolism of 6-mercaptopurine by resistant Escherichia coli cells. J. Bacteriol. 92:446-454. 1966.-6-Mercaptopurine (MP) utilization as a source of purine in MP-sensitive and -resistant cultures of Escherichia coli was investigated. The label of MP-8-C(14) appeared in adenine and guanine of ribon...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)70763-1